Fig. 5: Putative evolution analysis of SARS-CoV-2 Omicron spike protein.

a, Putative simulation of evolution and devolution paths. m_i/m_d represents mutating via modelinc/modeldec and the following number indicates the mutation round. b, DBSCAN clusters with regard to the first two principal components (PC-1 and -2). c, Heatmap of the first and second principal components from SGT embeddings.