Extended Data Fig. 3: Analyzing disease duration and onset age.
From: Data-driven discovery of movement-linked heterogeneity in neurodegenerative diseases
(A) Visualization of disease duration and onset age across subtypes (N = 30). For each box, the central line indicates the subtype median value, and the top and bottom edges indicate the 75th and 25th percentiles, respectively. The whiskers extend to 1.5 times the interquartile range, and data points beyond the whiskers are represented using the ♦ symbol. For the onset age variable which is significantly different between groups (P < 0.05 from Kruskal-Wallis test), each subtype mean value is overlayed as a gold × symbol, and dashed gold lines connect subtype mean values across subtypes. While disease duration is not significantly different across the three subtypes, onset age is significant and exhibits a pattern similar to the age variable. (B) Visualization of disease duration and age onset in our subtyping space. CCX signifies the motion component of our space. Each oval represents a single individual since there are multiple data points per individual.
