Extended Data Fig. 2: Overlaps between IN, IN+ and Casanovo’s correct predictions at 0.05 FDR for AC-PT and HC-PT. | Nature Machine Intelligence

Extended Data Fig. 2: Overlaps between IN, IN+ and Casanovo’s correct predictions at 0.05 FDR for AC-PT and HC-PT.

From: InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments

Extended Data Fig. 2

a, Peptide-level UpSet plot illustrating the intersection of correct predictions made by the IN, IN+, and Casanovo models on the AC-PT dataset, when evaluated at a false discovery rate (FDR) of 0.05. b, Peptide-level Venn Diagram illustrating the same intersections as figure a, but displaying them as percentages (recall) of the DB search ground truth dataset, which is illustrated by the area of the circle with the dotted edge. Areas in the Venn diagram are approximate, due to the imperfection of the Venn algorithm. c, Equivalent of figure a, for the HC-PT dataset d, Equivalent of figure b, for the HC-PT dataset.

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