Extended Data Fig. 7: Increased SCD activity and expression upon genetic modification.

a, Ratio of relative level of oleic/stearic acids in free fatty acids extracts from cells isolated from CNS of mice engrafted with SCD overexpressing (SCD-high, n=3 mice) and control (CTL, n=4 mice) 018z cells. p(two-tailed)=unpaired parametric Student’s t-test. b, Gene expression level of SCD after overexpression in REH cells (n=2 independent experiments). Error bars represent mean ± s.d.