Extended Data Fig. 7: Distinct β2m positive and negative areas in human cancers.
From: Long-distance modulation of bystander tumor cells by CD8+ T-cell-secreted IFN-γ
a, Immunohistochemical staining of β2m and b, β2m and CD8 proteins on FFPE tissue of indicated human tumors. Heterogeneous β2m signal was observed in 16/51 tumors analyzed, one representative slide per tumor (obtained from resection material) was assessed and representative images are depicted in a. a. Scale bars are 100 μm. Note that CD8+ T cells in tumors predominantly localize to β2m high regions, representative images are depicted in b. Scale bars are 250 μm.
