Extended Data Fig. 8: Germline events. | Nature Cancer

Extended Data Fig. 8: Germline events.

From: Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes

Extended Data Fig. 8: Germline events.The alternative text for this image may have been generated using AI.

a, Type and frequency of germline variants detected in the POG570 cohort (variants found in the 27 genes with germline events shown in Fig. 5a. b, Expression of genes in patients with germline events, compared to the POG570 cohort. A percentile less than 25th (0.25) indicates low expression. c, Exposure of signatures SBS30 and SBS18 in patients with germline, and germline and somatic variants, compared with the POG570 cohort.

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