Extended Data Fig. 9: Single T cell RNAseq cluster analysis.
From: The T cell differentiation landscape is shaped by tumour mutations in lung cancer

(a, b) UMAP dimension reduction plot of NSCLC CD4 (a) and CD8 (b) TIL single cell RNA sequencing data (2469 and 1508 cells respectively). Manually identified subsets are located in the upper panels of A and B. Clustering analysis reveals 10 CD4 and 10 CD8 subsets (lower panels). Relative expression (z-score) of selected genes is shown in the adjacent heatmaps (each column represents a single cell).