Extended Data Fig. 1: Overview of collected and analysed samples per patient.
a) Consort diagram detailing the flow of patients into the CAPTURE Study and number of samples collected for each timepoint up to data lock on 15/06/2021. Baseline, prior to first vaccine dose or within 14 days of vaccination; FU1, follow-up 1: 2-4 weeks post-first vaccine dose; FU2, follow-up 2: within 14 days prior to second vaccination; FU3, follow-up 3: 2-4 weeks post-second vaccine dose. b) Blue rectangles indicate that a samples were collected or analysed (A), grey rectangles indicate that samples were not collected or analysed (NA), red rectangles indicate that samples were excluded from ELISPOT analysis either because cell numbers were too low, or positive/negative control failed in ELISPOT assay. c) Sampling and analysis schema for ELISPOT analysis. PBMC, peripheral blood mononuclear cells. NA, Not available, A, Analysed/Received, E, excluded.
