Table 2 Oncological and medical history of patients positive for SARS-CoV-2

From: Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study

N = 118

Past medical history

HTN

31 (27)

PVD/IHD/CVD

9 (8)

Diabetes mellitus

14 (11)

Obesity, BMI > 30, n (%)

25 (21)

Inflammatory/autoimmune

7 (6)

Smoking status

 Current smoker

36 (31)

 Ex-smoker

51 (43)

 Never smoked

12 (10)

 Unknown

19 (16)

Oncological history

Solid tumors, n = 97

Disease status (in respect to last treatment)

SACT, palliative, n= 74

 CR/PR

27 (28)

 SD

24 (24)

 PD

23 (24)

SACT, neoadjuvant or radical CRT

8 (8)

Surgery±adjuvant SACT

15 (15)

Treatment within 12 weeks

Systemic therapy

 Chemotherapy

43 (44)

 Small molecule inhibitor

15 (15)

 Anti-PD-(L)1 ± anti-CTLA-4

14 (14)

 Endocrine therapy

7 (6)

 No treatment

5 (4)

Local therapy

 Surgery

15 (13)

 Radiotherapy

11 (10)

Hematological malignancies, n = 21

Diagnosis

 Acute leukemia

11 (52)

 Lymphoma

6 (29)

 Myeloma

4 (19)

Disease status

 MRD/CR

5 (24)

 Partial remission

7 (33)

 SD

3 (14)

 PD/relapse/untreated acute presentation

7 (33)

Treatment within 12 weeks

 Chemotherapy

17 (81)

 Targeted therapy

10 (48)

 Anti-CD20 therapy

6 (29)

 CAR-T

1 (5)

Hematological stem cell transplant

 Auto/allograft pre-COVID-19

6 (29)

 Auto/allograft post-COVID-19

2 (9)

  1. BMI, body mass index; CAR-T, chimeric antigen receptor T cell; CD20, B-lymphocyte antigen; CR, complete response; CRT, chemoradiotherapy; CTLA-4, cytotoxic T-lymphocyte-associated protein 4; CVD, cardiovascular disease; HTN, hypertension; IHD, ischemic heart disease; MRD, minimal residual disease; PD progressive disease; PR, partial response; PVD, peripheral vascular disease;SD, stable disease.