Extended Data Fig. 7: BayesPrism improves correlations between gene expression in reference and ground truth pseudo-bulk data in non-malignant cells. | Nature Cancer

Extended Data Fig. 7: BayesPrism improves correlations between gene expression in reference and ground truth pseudo-bulk data in non-malignant cells.

From: Cell type and gene expression deconvolution with BayesPrism enables Bayesian integrative analysis across bulk and single-cell RNA sequencing in oncology

Extended Data Fig. 7

Scatter plots show log2 gene expression in non-malignant cells from the original scRNA-seq reference φ (the left column) and the updated reference ψ after the information pooling step (the right column) versus the mean expression in scRNA-seq used to generate pseudo-bulk. Genes with zero expression counts in the scRNA-seq reference are colored in red, and those with non-zero expression counts are colored in blue.

Back to article page