Extended Data Fig. 9: Comparison between tumor purity inferred by BayesPrism, CIBERSORTx, ABSOLUTE, ESTIMATE and IHC. | Nature Cancer

Extended Data Fig. 9: Comparison between tumor purity inferred by BayesPrism, CIBERSORTx, ABSOLUTE, ESTIMATE and IHC.

From: Cell type and gene expression deconvolution with BayesPrism enables Bayesian integrative analysis across bulk and single-cell RNA sequencing in oncology

Extended Data Fig. 9

Boxplots show the correlation between malignant fractions inferred by each method for TCGA-GBM, TCGA-OV, TCGA-HNSCC, and TCGA-SKCM. Three statistics were computed: Pearson’s correlation coefficient (left column), Spearman’s correlation coefficient (center column), and mean squared error (right column). Statistics were computed between each method indicated by the x axis and the mean of ABSOLUTE scores from two sources (top row), ESTIMATE (center row), and IHC (bottom row). Boxes mark the 25th percentile (bottom of box), median (central bar), and 75th percentile (top of box). Whiskers represent extreme values within 1.5 fold of the inter quartile range.

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