Extended Data Fig. 9: Vaccination is associated with prolonged overall survival probability across patient subgroups, related to Fig. 4.
Forest-plot indicating hazard ratios (HR, squares) and 95% confidence intervals (CI, whiskers) of vaccinated (n = 26) and unvaccinated (n = 64) patients stratified into the subgroups indicated with the exact number (no.) of events and patients at risk for each subgroup as well as the 95% CIs indicated on the left. Hazard ratios and confidence intervals were calculated using a Log-rank test or if no events were observed in one group with the Mantel-Hanszel method. sex - female: test statistic = 3.2, sex - male: test statistic = 11.3, age ≤60: test statistic = 9.4, age >60: test statistic = 4.4, ECOG 0: test statistic = 2.0, ECOG > 0: test statistic = 10.6, tumor type = melanoma: test statistic = 5.1, tumor type = other: test statistic = 11.1, stage <4: test statistic = 14.9, stage 4: test statistic = 0.7, therapy = PD-1/PD-L1 mono: test statistic = 7.1, therapy = other: test statistic = 7.0, therapy line = 1st: test statistic = 3.1, therapy line = other: test statistic = 13.5, BMI > 25: test statistic = 8.8, BMI ≤ 25: test statistic = 8.2. Diagn.: diagnosis.
