Extended Data Fig. 8: Weights for the DyAM Rad+IHC-A + Gen+PD-L1 model.

Parameter weight results for combined radiomic, intensity-based PD-L1 texture, genomic and TPS features for the DyAM Rad+IHC-G + Gen model. The box-and-whisker plots show the mean and the interquartile range (25–75%) as boxes, the minimum and maximum as whiskers up to 1.5 times the IQR and datapoints outside the IQR range as diamonds, for N = 10 fits. The adjoined bar plot shows the number of times, for a given feature, the following criteria were satisfied: (1) if applicable, the feature was selected as part of the radiomics filtering process, (2) the magnitude of the feature’s weight was at least 1 standard deviation from zero and (3) the magnitude of the feature’s weight was greater than 0.01. Only coefficients selected more than once are shown, up to 100.