Extended Data Fig. 6: Glycolysis and the TCA cycle were slightly affected by nucleosides under low glucose conditions. | Nature Cancer

Extended Data Fig. 6: Glycolysis and the TCA cycle were slightly affected by nucleosides under low glucose conditions.

From: Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth

Extended Data Fig. 6: Glycolysis and the TCA cycle were slightly affected by nucleosides under low glucose conditions.The alternative text for this image may have been generated using AI.

(a, b) 14837 T cells were cultured in complete media (25 mM glucose), low glucose media (1 mM glucose) with or without uridine (U, 0.5 mM), inosine (I, 0.5 mM), adenosine (A, 0.5 mM), guanosine (G, 0.5 mM), cytidine (C, 0.5 mM) for 48 h. The cells were counted to calculate the cell proliferation (a). Metabolic analysis of cells was performed by mass spectrometry (b). Data are shown as mean ± SD. (n = 3 biologically independent samples). Statistical analysis was performed using ordinary one-way ANOVA with Tukey’s multiple comparisons test.

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