Extended Data Fig. 8: Increased numbers of monocytes/macrophages in response to irradiation in breast and rectal cancer.
From: Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect
a. Signature for the cell cycle status of CD45 + hematopoietic cells in the scRNA-seq datasets as in Fig. 4d. b. Absolute abundance of monocytes-macrophages, monocytes, M0, M1, and M2 macrophages, T cells, CD4+, CD8+, and regulatory T cells based on CIBERSORTx enumeration in human breast cancer and rectal cancer. n = 9 (Ctrl, RT) in breast cancer. n = 13 (Ctrl) and n = 9 (RT) in rectal cancer. Two-tailed parametric paired (breast cancer study) or unpaired (rectal cancer study) t-tests were performed in b and the actual values are indicated in addition to the asterisks. *p<0.05, **p<0.01. Error bars represent SEM.
