From the first engineered T cell receptor medicine to regulatory snubs over China-only data, 2022 was another action-packed year for the oncology drug development community.

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Change history
18 January 2023
In the version of this article initially published, there was an error in the last paragraph of the “Degraders make the grade” section, where in the text now reading “Among them, AstraZeneca announced positive results this October from a pair of studies showing that the oral SERD camizestrant improved progression-free survival...,” “camizestrant” appeared as “capivasertib”; the change has been made to the HTML and PDF versions of the article.
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Dolgin, E. Cancer drug approvals and setbacks in 2022. Nat Cancer 3, 1406–1408 (2022). https://doi.org/10.1038/s43018-022-00482-y
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DOI: https://doi.org/10.1038/s43018-022-00482-y