Extended Data Fig. 2: Correlations between CD8 IHC staining and RNA-seq deconvolution estimates. | Nature Cancer

Extended Data Fig. 2: Correlations between CD8 IHC staining and RNA-seq deconvolution estimates.

From: Multimodal immunogenomic biomarker analysis of tumors from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab

Extended Data Fig. 2

CD8 T-cell estimates (x-axes) were derived using six published immune deconvolution tools and compared to the percentage of CD8 staining (IHC, y-axes) from iMATRIX-atezo tumor tissue samples. Values represent the Spearman coefficients for each comparison. Colors denote sample origin as lymph node (brown) or one of the following: lung, soft tissues, bone, adrenal gland, kidney, brain, or unannotated tissue types (yellow) (N = 66 samples).

Back to article page