Extended Data Fig. 3: Patterns of expression of MM-preferential dependencies in MM vs non-MM cell lines. | Nature Cancer

Extended Data Fig. 3: Patterns of expression of MM-preferential dependencies in MM vs non-MM cell lines.

From: Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

Extended Data Fig. 3

RNA-Seq data (CCLE dataset) for MM-preferential dependencies in MM vs. non-MM cell lines. Transcript levels (log2(TPM + 1)) for each gene (row) across MM and non-MM cell lines are scaled by maximum value resulting in a value range between 0 and 1 and presented as stacked bar plots. Color bars on the side of the graph denote different clusters of genes, defined based on analyses of Fig. 3 (based on 2-sided limma t-test FDR and log2FC of differential expression of each gene in MM vs non-MM lines).

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