Extended Data Fig. 3: Expression of effector molecules, immune checkpoints, & cytotoxicity receptors.
From: γδ T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors
(a) Heatmap of effector gene expression in cell clusters from CRC samples. (b) Heatmap of immune checkpoint expression in cell clusters from CRC samples. (c) Heatmap of cytotoxicity receptor expression in cell clusters from CRC samples. (d) Production of IL17A in healthy colon and tumor γδ T cell subsets after PMA stimulation. Data presented as mean ± SEM. Data were analyzed using Friedman test, with Dunn’s multiple comparison test two tailed (n = 6 (Vδ3), 12 (Vδ2), 13 (Vδ1) patients, * p < 0.05, ** p < 0.01, ** p < 0.001).
