Extended Data Fig. 9: TLS characterization by spatial transcriptome. | Nature Cancer

Extended Data Fig. 9: TLS characterization by spatial transcriptome.

From: Integrative single-cell analysis of human colorectal cancer reveals patient stratification with distinct immune evasion mechanisms

Extended Data Fig. 9: TLS characterization by spatial transcriptome.The alt text for this image may have been generated using AI.

(a) Hematoxylin-eosin staining of tumor tissue sections (top) and spatial transcriptomic profiles of TLS 12 classical markers score (middle) and G6 signature genes score (bottom). This pattern was replicated in six patients, and one of them is shown in Fig. 7a. (b) LTB expression in spatial transcriptomic spots. This pattern was replicated in six patients, and one of them is shown in Fig. 7d.

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