Extended Data Fig. 4: Single-cell RNA-seq, TCR-seq and CITE-seq on 245,675 total T cells pooled from CT26 tumor, dLN and blood from 31 mice. | Nature Cancer

Extended Data Fig. 4: Single-cell RNA-seq, TCR-seq and CITE-seq on 245,675 total T cells pooled from CT26 tumor, dLN and blood from 31 mice.

From: TIGIT and PD-L1 co-blockade promotes clonal expansion of multipotent, non-exhausted antitumor T cells by facilitating co-stimulation

Extended Data Fig. 4

a, UMAP showing T cell clusters representing CD8+ T cells, CD4+ T cells and regulatory T cells. b,c. Treatment group (Group) (b) or tissue source (c) of T cells. d-g. CD8a expression (d), granzyme B expression (e), clone size (f), gp70 ADT counts (g) projected on UMAP. h, CITE-seq relative expression levels for indicated markers are projected on UMAP.

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