Extended Data Fig. 8: Characterization of tumor-specific CD8+ T cell cluster composition. | Nature Cancer

Extended Data Fig. 8: Characterization of tumor-specific CD8+ T cell cluster composition.

From: TIGIT and PD-L1 co-blockade promotes clonal expansion of multipotent, non-exhausted antitumor T cells by facilitating co-stimulation

Extended Data Fig. 8

CD8+ T cell cluster composition segregated by specificity for gp70, determined by comparing ADT counts for gp70 tetramers, requiring that they be higher than control tetramer count by a Poisson test with a one-sided p-value < 1×10-6. The proportion of each cluster within total CD8+ T cells from the indicated tissue for each treatment group is shown. Each symbol represents an individual mouse; each color identifies the same mouse within the treatment group.

Source data

Back to article page