Extended Data Fig. 1: Positive predictive value of PSA in ProtecT by P-CARE values stratified by PSA values. | Nature Cancer

Extended Data Fig. 1: Positive predictive value of PSA in ProtecT by P-CARE values stratified by PSA values.

From: Genomic risk model to implement precision prostate cancer screening in clinical care: the ProGRESS study

Extended Data Fig. 1

Illustrated are mean PPV (95% CI) for various PSA levels (all ( ≥ 3 ng/mL), 3–4 ng/mL, 4-10 ng/mL, and >10 ng/mL) for clinically significant prostate cancer among three groups of men in the ProtecT study (n = 6,411): all men (regardless of P-CARE value), men in the top 20% of P-CARE values (P-CARE80), and men in the top 5% of P-CARE values (P-CARE95). Abbreviations: CI, confidence interval; P-CARE, Prostate CA Risk and Evaluation; PPV, positive predictive value; ProtecT, Prostate Testing for Cancer and Treatment; PSA, prostate-specific antigen.

Source data

Back to article page