Extended Data Fig. 6: Diagnostic biopsy analysis of PT0761. | Nature Cancer

Extended Data Fig. 6: Diagnostic biopsy analysis of PT0761.

From: Neoadjuvant PD-1 blockade in surgically resectable desmoplastic melanoma: cohort A of the phase 2 SWOG S1512 trial

Extended Data Fig. 6: Diagnostic biopsy analysis of PT0761.The alternative text for this image may have been generated using AI.

This case has evidence of two different histologies of melanoma, which may be co-primary melanomas at the same site. A) Low power image of the specimen by H&E and S100 IHC, showing a dense sheet of S100 positive epithelioid melanoma cells in the left side, with evidence of radial growth phase and an in situ component (higher power image in B), and an area in the right of the specimen with desmoplastic melanoma of pure histology (high power image in C).

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