Fig. 1: From wood to composite: synthesis pathway from wood to BGPGMA monomer, as compared to conventional BisGMA synthesis, towards the development of a new generation of bio-based dental composite.
From: Lignin-derived bisguaiacol P vinyl ester as a bisphenol A-free resin alternative
Both BisGMA and BGPGMA were synthesized through three downstream reactions that follow the upstream (bio)refinery process, including dimerization of the respective fossil-based bisphenol (i.e., phenol, acetone) or bio-based bisguaiacol (i.e., isoeugenol, guaiacol) precursors, epoxidation, and esterification. A composite matrix was produced by mixing BGPGMA (or BisGMA) with TEGDMA and the CQ/EDMAB photo-initiation system. Barium-borosilicate glass filler was vacuum-mixed into the matrix to generate the bio-based composite.
