Fig. 3: Along-tract anomalies in a single patient. | Nature Computational Science

Fig. 3: Along-tract anomalies in a single patient.

From: Detecting microstructural deviations in individuals with deep diffusion MRI tractometry

Fig. 3

Reconstructed tract profiles of CNV (top) and typically developing (bottom) patients reveals RISH0 discrepancies along various association bundles such as the AF, ILF and SLF. The marked pink areas represent sections along the bundle where anomalies are detected by the leave-one-out cross-validation approach (threshold = 1 per number of healthy participants). Specifically, the autoencoder is trained using healthy participant data only, and compared with the FCD patient. Then for each of the healthy participants, the FCD patient is shuffled back in the population and the newly left out healthy participant is compared with that population. We then assess the MAE. The letters correspond to the tract list found in the Supplementary Information.

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