Extended Data Fig. 8: Ancestor-Descendant (AD) and Different Lineages (DL) accuracy measures, as well as the running time distributions for HUNTRESS on large simulated datasets.
From: Fast intratumor heterogeneity inference from single-cell sequencing data
In these simulations we set n=5000, m=500, fn=0.05 or 0.2, fp=0.001 and na=0.05. For each setting, the distributions are reported over 10 distinct trees of tumor progression. Note that because ScisTree could not finish any of the tasks within the time limit of 48 hours and SPhyR failed to generate any output, they are not presented in the figure. Note that each (violin) plot shows the maximum, center and minimum value of the data depicted, together with the probability density.
