Extended Data Fig. 1: A running time assessment of HUNTRESS on simulated data with no false positives, in comparison to ScisTree, SPhyR, and PhISCS-BnB, as well as its slower but more general variants, PhISCS-I, and PhISCS-B.
From: Fast intratumor heterogeneity inference from single-cell sequencing data
All numbers on y-axis are in log10 scale. Here n, m and fn, respectively, denote the number of cells, the number of mutations and the false negative error rate in single-cell data. For each setting of n and m, we report the distribution of the running time for each tool - over 10 distinct trees of tumor progression, with false negative error rates of 0.05, 0.1 and 0.2. Each tool was run with a time limit of 8 hours (those cases that exceed the time limit are not included here). The corresponding accuracy measures for each setting are shown in Extended Data Figure 2 (ancestor descendant accuracy measure) and Extended Data Figure 3 (different-lineages accuracy measure).
