Fig. 4: MAGICAL-identified circuit genes robustly predict S. aureus infection and bacteria antibody sensitivity.
From: Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data
a, Circuit genes in common to MRSA and MSSA infections achieved a near-perfect classification of S. aureus infected and uninfected samples in multiple independent datasets (one adult dataset and two pediatric datasets). b, Circuit genes that differed between MRSA and MSSA showed predictive value of antibiotic sensitivity in independent patient samples (three pediatric datasets).
