Fig. 3: Antidepressants increase the cell membrane permeability of A. baylyi ADP1. | ISME Communications

Fig. 3: Antidepressants increase the cell membrane permeability of A. baylyi ADP1.

From: Antidepressants promote the spread of extracellular antibiotic resistance genes via transformation

Fig. 3: Antidepressants increase the cell membrane permeability of A. baylyi ADP1.

a Cell membrane permeability of A. baylyi ADP1 after 6 h treatments of various antidepressants (n = 9). Heat-maps showing the transcriptional changes (b) and translational changes (c) of outer membrane assemble and porin-related genes under the exposure to various antidepressants (n = 3). d Comparisons between antidepressants-mediated membrane permeability under aerobic and anaerobic conditions (n = 9). Significant differences between individual antidepressant-treated groups and the control groups (0 mg/L) were analysed with ANOVA and shown with * (padj < 0.05) or ** (padj < 0.01). P values were corrected by the Benjamini/Hochberg method.

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