Fig. 4: Proposed model of carbohydrate metabolism shift in coral microbiomes under acidification conditions, from direct energy production to structural maintenance pathways.

KEGG pathways and KO entries showing acidification related modifications in relative abundance or prevalence, respectively, are reported in rectangles using the same color code of the coral compartment in which variations were observed (mucus, yellow; soft tissue, green; skeleton, gray). Upward and downward arrows indicate that the KEGG pathway increased or decreased in terms of relative abundance with the increasing acidification, respectively. Reported KO entries (*) were detected in all replicates from the highly acidified site while absent in samples from control sites. Cell functions hypothesized to be connected with the variations of KEGG pathways abundance and KO entries detection are reported in dashed circles. Dotted arrows represent the influence of acidification on carbohydrates utilization. Dashed arrows represent connections between observed increasing/decreasing pathways and cell functions. Abbreviations: LPS lipopolysaccharides; Ala Alanine; Asp Aspartate; Glu Glutamate.