Fig. 1: Change in genetic diversity due to a hypothetical treatment that increases mutation rate (x10) but decreases population size (/100).
From: Ecological effects of stress drive bacterial evolvability under sub-inhibitory antibiotic treatments
The left panel shows the distribution of the number of mutants in the final population for 1000 simulations. The right panel shows the distribution of the number of mutational events in the same simulations. The number of mutational events gives a more precise estimation of genetic diversity, because a single mutational event can give several times the same mutant in the final population. The number of (non-unique) mutants, however, can be directly measured experimentally.
