Fig. 2: Effect of antibiotic treatments on estimated mutation rate and population size.

Different antibiotics are shown in different columns on the x axis, ordered by class. Colours indicate different studies (ten datasets from the literature plus our data). A single study may comprise several data points associated with the same antibiotic because several doses were tested or because several biological replicates (each of them comprising several parallel replicate populations) were performed. A Effect of antibiotic treatments on estimated mutation rate, under the assumption that there is no cell death. All mutation rates are relative to the untreated control (rel. NT, horizontal line y = 1). The mutation rates were estimated using rSalvador [29]. B Effect of antibiotic treatments on population size. All population sizes are relative to the untreated control (horizontal line y = 1). Each data point represents the average final population size in several parallel replicate populations treated with a specific dose of a given antibiotic.