Fig. 4: MD simulation—WF peptides penetrate POPG bilayers more readily than POPE/POPG bilayers.
From: Synergy between Winter Flounder antimicrobial peptides
Sideview snapshots for WF2/pleurocidin after 200 ns in POPG (a) or POPE/POPG (b) bilayers—for clarity only the phosphorus atoms are shown for the lipids. Centre of Mass (COM) is shown as averages of the four peptides in each simulation over the last 100 ns in each of three (WF and pleu-KR) or two (temporin L) replicate 200 ns simulations (c). Mean and SE shown for replicates. Two-way ANOVA with Šídák’s multiple comparisons test: *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.
