Table 2 Point mutation in QRDR and sequence type (ST) of the E. coli strains at the start of the long-term exposure T = 0 and after treatment with flumequine or enrofloxacin at T = 9
T = 0 | T = 9 flumequine | T = 9 enrofloxacin | ||||
|---|---|---|---|---|---|---|
Strain | Amino acid substitution | ST | Amino acid substitution | ST | Amino acid substitution | ST |
WGS-ecoli-sample-38 | - | 5334 | GyrA A119Ea | 5334 | Unknown | 5334 |
WGS-ecoli-sample-46 | - | 349 | GyrA D87H | 349 | GyrA D87G | 349 |
WGS-ecoli-sample-47 | - | 8070 | GyrA D87Y | 8070 | GryA D678Ea | 8070 |
WGS-ecoli-sample-49 | - | 58 | GyrA D87G | 58(SLV) | GyrA D87G | 58 |
WGS-ecoli-sample-64 | - | 4642 | GyrA D87G | 4642 | GyrA D87G | 4642 |
WGS-ecoli-sample-70 | - | 2307 | GyrA D87G | 2307 | GyrA D87G | 2307(DLV) |
WGS-ecoli-sample-88 | - | 40 | GyrA L447Ma | 40 | GyrA D87G | 40 |
WGS-ecoli-sample-107 | - | 101 | GyrA E153Ga | 101 | GyrA D87G | 101 |
WGS-ecoli-sample-113 | - | 720 | ParC S57T | 720(SLV) | GyrA D87Y, ParC S57T | 720 |
WGS-ecoli-sample-99 (Control) | GyrA S83L | 752 | GyrA S83L | 752 | GyrA S83L | 752 |
