Fig. 9: Siderophore conjugation strategies exploiting bacterial biochemistry. | npj Antimicrobials and Resistance

Fig. 9: Siderophore conjugation strategies exploiting bacterial biochemistry.

From: Siderophores as tools and treatments

Fig. 9

A Trimethyl locks synthesised by Miller et al. Q represents a quinolone. B Glutathione initiated disulfide cleavage and oxothiolanone cyclisation. Q represents a quinolone. C Reaction scheme of the β-lactamase initiated ring opening cascade culminating in the release of the oxazolidinone (inset). Chemdraw Professional version 22.2.0.3300.

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