Fig. 5: Population comparison based on azole-resistance. | npj Antimicrobials and Resistance

Fig. 5: Population comparison based on azole-resistance.

From: Aspergillus fumigatus mitogenomes and their influence on azole-resistant and -susceptible populations

Fig. 5

a Phylogenetic tree with bootstrap support based on SNPs in nuclear encoded mitochondrial genes. Resistance phenotype, Cyp51A genotype and country of origin are highlighted by coloured boxes and the absence of the genes pet8 and aifA are indicated by coloured circles. Clades A and B are highlighted by orange and pink bands, respectively. Tree scale represents nucleotide substitution per site. b Accessory genes significantly associated with resistance identified by Scoary and their occurrence according to phenotype. c Violin-plot and boxplot of mitochondrial DNA copy number comparing resistant and susceptible isolates, with p-value indicated for the Pairwise comparisons using Wilcoxon rank sum exact test and Bonferroni adjustment method.

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