Fig. 3: Effect of Aurodox on faecal shedding and histological markers of C. rodentium in the distal colon. | npj Antimicrobials and Resistance

Fig. 3: Effect of Aurodox on faecal shedding and histological markers of C. rodentium in the distal colon.

From: Evaluating the protective effects of Aurodox in a murine model of Shiga toxin-producing Escherichia coli

Fig. 3

A Faecal shedding in Aurodox-treated (n = 8) versus PBS-treated mice (n = 8) over seven days. B Change in weight of Aurodox-treated vs corn oil-treated mice between day 6 and day 10. C H & E stained sections of colons recovered from Aurodox versus PBS-treated mice, orange box shows area displayed at higher magnification. D Violin plot depicting crypt length of Aurodox-treated mice vs vehicle-treated mice at 10 dpi. Ten measurements were taken from two colon sections per animal (n = 80 per group). * indicates p < 0.05, **indicated p < 0.005 and *** indicated p < 0.001 as determined by paired t-test.

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