Table 1 Complete profile of the selected compounds

From: A three-dimensional high throughput assay identifies novel antibacterial molecules with activity against intracellular Shigella

  1. Key: Green: MW ≤ 400; Chromlog ≤4; PFI ≤ 6; Permeability high, pIC50 ≥ 5; Selectivity ≥1; CAD solubility ≥100. Yellow: MW 400–500; Chromlog 4–6; PFI 6–9; Permeability medium; CAD solubility ≥ 30–100. Red: MW ≥ 450; Chromlog ≥6; PFI ≥ 9; Permeability low; Cytotox HepG2 ≥ 4.5; Selectivity ≤0.5; CAD solubility ≤30.
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