Fig. 2: Most widely used drugs in human and veterinary medicine for the treatment of apicomplexan infections.
From: A review of natural products as a source of next-generation drugs against apicomplexan parasites
Around 39% are natural products or chemically modified derivatives (semi-synthetic), and a further 22% are synthetic compounds inspired by natural pharmacophores. Clinical resistance has emerged to the majority of these drugs, leaving few alternatives with strong therapeutic potential available.
