Fig. 9: Different types of incentive strategies as a solution to promote antibiotic R&D.
From: Current economic and regulatory challenges in developing antibiotics for Gram-negative bacteria
The figure highlights economic strategies to promote antibiotic R&D, categorised into four domains. Push incentives include tax benefits, research grants, public-private partnerships, venture capital funding, and collaborative initiatives targeting early-stage R&D support. Pull incentives focus on market entry rewards, tradeable exclusivity vouchers, volume-delinked payment models, and diagnosis-related groups, offering financial returns post-market approval. Mixed incentives and other models combine approaches like options market awards, antibiotic taxing, and tailored policies to bridge funding gaps. Other potential strategies suggest a two-pronged approach, council formation for antibiotic oversight, and an antibiotic susceptibility bonus. These measures collectively aim to address the financial challenges limiting antibiotic innovation and facilitate sustainable R&D investments.
