Fig. 4: Functional annotation and protein-protein interactions prediction of differentially abundant proteins (DAPs) in S. aureus NCTC8325 under sub-MIC of chloramphenicol treatment. | npj Antimicrobials and Resistance

Fig. 4: Functional annotation and protein-protein interactions prediction of differentially abundant proteins (DAPs) in S. aureus NCTC8325 under sub-MIC of chloramphenicol treatment.

From: Proteomic and metabolomic responses of priority bacterial pathogens to subinhibitory concentration of antibiotics

Fig. 4: Functional annotation and protein-protein interactions prediction of differentially abundant proteins (DAPs) in S. aureus NCTC8325 under sub-MIC of chloramphenicol treatment.

a presents gene ontology (GO) terms significantly enriched in proteins decreased in abundance and (b) proteins increased in abundance. The coloured scale on the right represents negative logarithmic scale with a base 10 of false discovery rate (FDR) values for each of these terms. c presents STRING network of DAPs. Coloured scale on the bottom left refers to logarithmic scale with a base 2 of fold changes for each of these DAPs with blue colour denoting proteins decreased in abundance and red denoting proteins increased in abundance. Coloured ellipses represent subnetworks represented by GO term, KEGG pathway or STRING cluster enriched with DAPs. Abbreviations: MF molecular function, CC cell compartment, BP biological process.

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