Table 3 Total number of intracellular (IC) or extracellular (EC) metabolites significantly increased or decreased in abundance and their total number in Klebsiella pneumoniae NCTC418 and Escherichia coli MG1655 treated with kanamycin, imipenem, cefotaxime or ciprofloxacin relative to the control treatment

From: Proteomic and metabolomic responses of priority bacterial pathogens to subinhibitory concentration of antibiotics

  

KANa vs. CTa

IMIa vs. CT

CTXa vs. CT

CPFXa vs. CT

Species

CCa

Upa

Downa

ÎŁa

Up

Down

ÎŁ

Up

Down

ÎŁ

Up

Down

ÎŁ

NCTC418

IC

9

1

9

13

1

14

7

2

9

7

1

8

 

EC

14

3

17

7

3

10

4

2

6

3

8

11

MG1655

IC

7

2

9

7

2

9

2

1

3

9

2

11

 

EC

14

3

17

7

1

8

8

1

9

5

1

6

  1. aCC cellular compartment, IC intracellular, EC extracellular, KAN kanamycin, CT control, IMI imipenem, CTX cefotaxime, CPFX ciprofloxacin, ÎŁ total number of altered metabolites highlighted in bold, Up increased in abundance, Down decreased in abundance.
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