Fig. 3: Whole genome sequencing analysis in the three lesions. | BJC Reports

Fig. 3: Whole genome sequencing analysis in the three lesions.

From: Transdifferentiation of cervical squamous cell carcinoma with ERBB2 amplification to adenocarcinoma: whole genome sequence analysis and successful control by anti-HER2 therapy

Fig. 3

a A Venn diagram indicating the number of mutations in CeSq, SiSq, and PeAd and their containment relationships. b A Venn diagram indicating the number of copy number variations (≥4 copies) in CeSq, SiSq, and PeAd and their containment relationships. c Summary of the functional analysis of whole genome sequencing. Functionally deleterious mutations of PRDM2, RXRB, TPR, and ZNF845 are shared among CeSq, SiSq, and PeAd. Their variant allele frequencies (VAFs) in each specimen are shown in the table.

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