Fig. 3: Comparison of EC clusters between previously published ccRCC scRNA-seq and this study. | BJC Reports

Fig. 3: Comparison of EC clusters between previously published ccRCC scRNA-seq and this study.

From: Single cell atlas of kidney cancer endothelial cells reveals distinct expression profiles and phenotypes

Fig. 3

a UMAP plot of integrated NEC and TEC populations from ccRCC in previously published studies and this study. The dashed line indicates the cells that are clustered in the common clusters. b Overlap between differentially expressed genes (compared to NAT, cutoffs at logFC = 0.25, minimum detection fraction = 0.1) in two previously published studies and this study. c Common reactome pathways that are derived from the overlapped DEGs in TECs. d UMAP plot colored by tissue origin of previously published datasets and this dataset. e IGFBP3 and IGFBP5 expression in TECs and NECs.

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