Fig. 1: Comparison between previous and updated BOADICEA parameters, and between the corresponding predicted BC risks. | BJC Reports

Fig. 1: Comparison between previous and updated BOADICEA parameters, and between the corresponding predicted BC risks.

From: BOADICEA model: updates to the BRCA2 breast cancer risks for ages 60 years and older

Fig. 1

a Previous and updated BRCA2 relative risks in BOADICEA/CanRisk v2.4. b Previous and updated BC incidences for BRCA2 mutation carriers (UK cohort born in 2000). c Revised cumulative breast cancer risk for the average BRCA2 pathogenic variant (PV) carrier (20 years old, born in 2000) using previous and updated BRCA2 RRs. d Corresponding cumulative risks for BRCA2 PV carrier (20 years old, born in 2000) with an affected mother (40 years old, born in 1980) diagnosed at age 40.

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