Table 5 Minor allele frequency by ethnics and estimated effect on the response to androgen deprivation therapy.

From: Predictive model of castration resistance in advanced prostate cancer by machine learning using genetic and clinical data: KYUCOG-1401-A study

SNP identification

Coefficient

1000 Genome

SAS

AFR

EUR

AMR

EAS

rs12979986

−1

0.26

0.08

0.34

0.34

0.21

rs9625031

−1

0.14

0.02

0.29

0.19

0.23

rs1931229

−1

0.35

0.10

0.28

0.33

0.50

rs1660281

1

0.26

0.49

0.11

0.21

0.38

rs10064620

1

0.41

0.26

0.37

0.32

0.26

rs10860210

−1

0.45

0.50

0.38

0.46

0.32

rs941207

1

0.16

0.08

0.26

0.25

0.26

rs9868579

−1

NA

NA

NA

NA

NA

rs62174680

1

0.29

0.03

0.32

0.28

0.34

rs11232056

1

0.26

0.28

0.17

0.41

0.47

rs8124833

1

0.10

0.20

0.13

0.25

0.39

rs74522810

−1

0.20

0.18

0.21

0.18

0.18

rs74369678

−1

NA

NA

NA

NA

NA

NA (chr3:74213366)

1

NA

NA

NA

NA

NA

rs2035081

−1

0.22

0.33

0.38

0.33

0.26

rs79404120

1

0.17

0.01

0.14

0.11

0.16

rs11672661

−1

0.40

0.06

0.48

0.48

0.43

rs28625772

1

0.05

0.30

0.06

0.07

0.08

rs9298681

1

0.24

0.47

0.20

0.45

0.26

Estimated effect

 

−0.16

1.70

−1.20

0.08

0.94

  1. AFR Africa, AMR native Americans, EAS East Asia, EUR Europe, NA not available, SAS South Asia, SNP single nucleotide polymorphism.
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