Fig. 4: Comparison of TS activity in liver parenchyma (upper panel) and metastases (lower panel) after intravenous bolus injections of 60 mg/m2 LV (LV60), 30 mg/m2 Arfo (A30), or 120 mg/m2 Arfo (A120) followed by bolus injections of 500 mg/m2 5-FU. | BJC Reports

Fig. 4: Comparison of TS activity in liver parenchyma (upper panel) and metastases (lower panel) after intravenous bolus injections of 60 mg/m2 LV (LV60), 30 mg/m2 Arfo (A30), or 120 mg/m2 Arfo (A120) followed by bolus injections of 500 mg/m2 5-FU.

From: Increased potentiation of 5-fluorouracil induced thymidylate synthase inhibition by 5,10-methylenetetrahydrofolate (arfolitixorin) compared to leucovorin in patients with colorectal liver metastases; The Modelle-001 Trial

Fig. 4

Data were lacking from two patients in the LV60 group. Symbols represents individual values.

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