Table 1 CT derived body composition measures and thresholds used and Systemic Inflammatory Grade (SIG) Calculation.

From: The relationship between tumour necrosis, systemic inflammation, body composition and survival in patients with colon cancer

Body composition measurement

High SFI [17]:

Males > 50.0 cm2m2 and Females > 42.0 cm2m2

Visceral obesity [20, 21]:

VFA : Males >160 cm2 and Females >80 cm2

Sarcopenia

SMI (Martin) [21]:

Males: BMI ≤ 25 kg/m2 and SMI < 43 cm2m2 or BMI > 25 kg/m2 and SMI < 53 cm2m2

Females: BMI ≤ 25 kg/m2 and SMI < 41 cm2m2 or BMI > 25 kg/m2 and SMI < 41 cm2m2

SMI (Dolan BMI > 25) [1]:

Males: BMI ≤ 25 kg/m2 and SMI < 45 cm2m2 or BMI > 25 kg/m2 and SMI < 53 cm2m2

Females: BMI ≤ 25 kg/m2 and SMI < 39 cm2m2 or BMI > 25 kg/m2 and SMI < 41 cm2m2

Myosteatosis

SMD (Martin) [21]:

BMI ≤ 25 kg/m2 and SMD < 41 HU or BMI > 25 kg/m2 and SMD < 33HU

SMD (Dolan BMI > 25) [1]:

BMI ≤ 25 kg/m2 and SMD < 34 HU or BMI > 25 kg/m2 and SMD < 32HU

SIG: Systemic Inflammatory Grade:

mGPS

Score

C-reactive protein ≤ 10

0

C-reactive protein > 10 and albumin ≥ 35

1

C-reactive protein > 10 and albumin < 35

2

NLR

NLR  <  3

0

NLR 3–5

1

NLR  >  5

2

Systemic Inflammatory Grade (SIG)

SIG 0

mGPS 0 and NLR  <  3

SIG 1

mGPS 0 and NLR 3–5 or mGPS 1 and NLR  <  3

SIG 2

mGPS 0 and NLR  >  5 or mGPS 2 and NLR  <  3 or mGPS 1 and NLR 3–5

SIG 3

mGPS 1 and NLR  >  5 or mGPS 2 and NLR 3–5

SIG 4

mGPS 2 and NLR  >  5

  1. SFI Subcutaneous Fat Index (subcutaneous obesity), VFA Visceral Fat Area (visceral obesity), SMI Skeletal Muscle Index (sarcopenia), SMD Skeletal Muscle Density (myosteatosis), mGPS modified Glasgow Prognostic Score, NLR Neutrophil Lymphocyte Ratio, SIG Systemic Inflammatory Grade.
Back to article page