Table 2 Treatment encounter characteristics in each year of treatment.
Year of treatment | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | |
Number | 250 | 13 | 3 | 4 | 6 | 8 | 12 | 9 | 5 | 11 | 15 | 10 | 16 | 21 | 17 | 17 | 25 | 35 | 23 |
First cycle (%) | 40 (16) | 5 (38) | 0 | 0 | 1 (17) | 3 (38) | 4 (33) | 1 (11) | 2 (40) | 4 (36) | 3 (20) | 2 (20) | 2 (13) | 1 (5) | 0 | 1 (6) | 5 (20) | 4 (11) | 2 (9) |
Line of treatment (%) | |||||||||||||||||||
First line | 136 (54) | 9 (69) | 2 (67) | 2 (50) | 4 (67) | 7 (88) | 7 (58) | 7 (78) | 3 (60) | 10 (91) | 12 (80) | 7 (70) | 6 (38) | 12 (57) | 8 (47) | 5 (29) | 9 (36) | 15 (43) | 11 (48) |
Second line | 29 (12) | 4 (31) | 1 (33) | 1 (25) | 2 (33) | 1 (13) | 2 (17) | 1 (11) | 1 (20) | 0 | 3 (20) | 1 (10) | 2 (13) | 2 (10) | 0 | 1 (6) | 2 (8) | 3 (9) | 2 (9) |
Third line | 5 (2) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 (6) | 1 (5) | 1 (6) | 0 | 1 (4) | 1 (3) | 0 |
Maintenance | 80 (32) | 0 | 0 | 1 (25) | 0 | 0 | 3 (25) | 1 (11) | 1 (20) | 1 (9) | 0 | 2 (20) | 9 (44) | 6 (29) | 8 (47) | 11 (65) | 13 (52) | 16 (46) | 10 (43) |
Type of SACT (%) | |||||||||||||||||||
Single-agent chemotherapy | 50 (20) | 6 (46) | 2 (67) | 2 (50) | 1 (17) | 1 (13) | 4 (33) | 1 (11) | 2 (40) | 2 (18) | 1 (7) | 4 (40) | 7 (44) | 3 (14) | 2 (12) | 4 (24) | 5 (20) | 2 (6) | 1 (4) |
Platinum-based doublet | 83 (33) | 5 (46) | 1 (33) | 2 (50) | 4 (67) | 7 (88) | 7 (58) | 6 (67) | 2 (40) | 8 (73) | 11 (73) | 5 (50) | 2 (12) | 6 (29) | 4 (24) | 3 (18) | 2 (8) | 6 (17) | 2 (9) |
Single agent IO | 69 (28) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 (20) | 1 (10) | 7 (44) | 12 (57) | 11 (65) | 10 (59) | 6 (24) | 7 (20) | 12 (52) |
Chemotherapy & IO | 40 (16) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12 (48) | 20 (57) | 8 (35) |
Other | 8 (3) | 2 (15) | 0 | 0 | 1 (17) | 0 | 1 (8) | 2 (22) | 1 (20) | 1 (9) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |